Imagine the scenario: There’s 2 patients. One is connected to a morphine drip while he’s reading a book and the other is being given a morphine injection by the doctor. They’re both given morphine at the exact same time. One is aware of it but the other isn’t.
You’d think they’d both need the same amount of the drug, wouldn’t you? Well, it turns out that how much they actually need depends on whether they know about the morphine or not.
On average, people receiving morphine for pain need about 12mg to get the painkilling effect. But that’s only if they don’t know they’re getting it. If it’s administered in full view, they don’t need nearly so much to get the same effect.
The same kind of thing has been shown with diazepam. People sometimes get diazepam for anxiety after an operation. It turns out that the diazepam only works if the patients know they’re receiving it. If they don’t know they’re getting it then it doesn’t work. Weird isn’t it?
The reason is that it’s all in your mind!
Chemistry will play itself out in exactly the same way a hundred times out of a hundred in a test tube. But once you put human consciousness in the test tube, in other words the test tube is technically the human body, the chemistry is swayed left or right, so to speak, depending on what’s going on in your mind, depending on what you believe.
It’s true. What we believe shifts chemistry in our brains and bodies. If a person is given a placebo instead of morphine, but believes that it’s morphine and therefore believes in the pain killing effect, their brain produces a natural version of morphine to carry out the job of giving them what they are expecting to happen, i.e. a reduction in pain. The natural versions are known as endogenous opiates.
So when a person is receiving morphine from the doctor, who is administering it in plain sight, their belief in what morphine does produces endogenous opiates. So because the endogenous opiates are there to provide part of the pain killing effect, the patient doesn’t actually need as much morphine.
Imagine what it could mean for medicine if we could harness the placebo effect like this.